Vandals poured powdered drinks and flour through corridors and daubed graffiti onto the walls of a kindergarten in Bettembourg.
The incident occurred sometime between Tuesday night at 9pm and Wednesday morning at 7.15am.
Staff at the crèche arrived at work on Wednesday to find a trail of powder in the halls and tags sprayed on walls and floors.
It is not known how the vandals entered the building. Anyone with information about the incident is urged to call police on 113.
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